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Histamine Key to Waking, Study Finds

Brain cells that contain the chemical histamine are critical for waking, scientists reported on Wednesday in a study that sheds light on conditions such as narcolepsy.

Their finding, published in this week's issue of the journal Neuron, also helps explain why antihistamines make many people sleepy.

"Our findings greatly improve our understanding of the brain activity responsible for maintaining consciousness and muscle tone while awake," said Dr. Jerome Siegel, of the University of California Los Angeles Neuropsychiatric Institute, who led the study.

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