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Resistant Strain of Syphilis Found

A fast-spreading mutant strain of syphilis has proved resistant to the antibiotic pills that are offered to some patients as an alternative to painful penicillin shots.

Since the late 1990s, doctors and public health clinics have been giving azithromycin to some syphilis patients because the long-acting antibiotic pill was highly effective and easy to use. Four pills taken at once were usually enough to cure syphilis.

But now researchers at University of Washington in Seattle have found at least 10 percent of syphilis samples from patients at sexually transmitted disease clinics in four cities had a strain resistant to azithromycin.

[...] Penicillin has long been the recommended treatment for syphilis. But it must be given in two buttocks injections much more painful than typical shots, because a large amount of the solution must be forced into the muscle.

[...] Lukehardt studied 114 syphilis samples from Seattle, San Francisco, Baltimore and Dublin, Ireland, finding 28 percent were resistant to azithromycin, including 88 percent of the Dublin samples.
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