Mmm... tastes like pork
Apr. 12th, 2003 02:26 pmHuman cannibalism was once common, prion gene suggests
Early humans may have regularly dined on each other.
That is the unappetizing conclusion of British researchers who have discovered that a gene that protects against prion diseases -- infectious diseases that can be spread through eating contaminated flesh -- is found in people all over the world.
The gene is most common among the Fore of Papua New Guinea who, until the late 1950s, feasted on the flesh of the dead at funerals. The Fore also suffered from kuru, an infectious disease that leads to tremors and dementia, and kills its victims within two years.
Researchers now know kuru is transmitted by a prion, a deviant protein that causes other proteins to clump together in the brain. They also know that it belongs to a group of diseases that includes bovine spongiform encephalopathy (sometimes known as mad-cow disease) and its human version, new variant Creutzfeldt-Jakob disease. All three leave the brains of victims riddled with holes.
Unless you happen to carry a protective gene.
The British team, whose results were published in today's issue of the journal Science, found that gene was most prevalent in female Fore over 50 who had survived years of mortuary feasting without getting kuru.
British people who carry the gene also seem to be protected from new variant Creutzfeldt-Jakob disease.
[…]The British researchers, led by John Collinge of University College in London, wanted to know how common the protective prion gene is, so they checked more than 2,000 DNA samples selected to represent worldwide genetic diversity.
They found a version of the gene in all populations, with its prevalence decreasing in East Asia except for the Fore.
This led them to conclude the gene may have evolved because it offered protection to human cannibals, and that cannibalism must have been widespread early in human history.( Read more... )
Early humans may have regularly dined on each other.
That is the unappetizing conclusion of British researchers who have discovered that a gene that protects against prion diseases -- infectious diseases that can be spread through eating contaminated flesh -- is found in people all over the world.
The gene is most common among the Fore of Papua New Guinea who, until the late 1950s, feasted on the flesh of the dead at funerals. The Fore also suffered from kuru, an infectious disease that leads to tremors and dementia, and kills its victims within two years.
Researchers now know kuru is transmitted by a prion, a deviant protein that causes other proteins to clump together in the brain. They also know that it belongs to a group of diseases that includes bovine spongiform encephalopathy (sometimes known as mad-cow disease) and its human version, new variant Creutzfeldt-Jakob disease. All three leave the brains of victims riddled with holes.
Unless you happen to carry a protective gene.
The British team, whose results were published in today's issue of the journal Science, found that gene was most prevalent in female Fore over 50 who had survived years of mortuary feasting without getting kuru.
British people who carry the gene also seem to be protected from new variant Creutzfeldt-Jakob disease.
[…]The British researchers, led by John Collinge of University College in London, wanted to know how common the protective prion gene is, so they checked more than 2,000 DNA samples selected to represent worldwide genetic diversity.
They found a version of the gene in all populations, with its prevalence decreasing in East Asia except for the Fore.
This led them to conclude the gene may have evolved because it offered protection to human cannibals, and that cannibalism must have been widespread early in human history.( Read more... )